Natural Clinoptilolite and Chabazite as Carriers for Antibacterial Agents: Cetylpyridinium Chloride (CPC) and Silver
Natural Clinoptilolite and Chabazite as Carriers for Antibacterial Agents: Cetylpyridinium Chloride (CPC) and Silver
Abstract
Natural clinoptilolite (Cli) and chabazite (Cha) were used as carriers for two types of antibacterial agents: cetylpyridinium chloride (CPC) and silver cations (Ag). CPC-zeolites, Ag-zeolites and CPC-Ag-zeolites were characterised using an energy-dispersive X-ray (EDX) analyser and Fourier transform infrared (FTIR) spectroscopy, confirming the attachment of CPC molecules to the Ag-zeolite in the CPC-Ag-zeolite samples. The minimum inhibitory concentration (MIC) against *P. aeruginosa* and *B. subtilis* in saline solution and distilled water was determined to investigate the effect of chloride ions on the antibacterial activity of the samples studied. Based on the MIC values, a new modified zeolite containing CPC and Ag (CPC-Ag-zeolites) exhibited better antibacterial activity than that of CPC-zeolites and Ag-zeolites, and performed well in both saline solution and distilled water.
Source: www.scientific.net